Recently, the non-traditional stable isotopic geochemistry has achieved great advancement in the study of the evolution of paleo-oceanic environment, in which the stable isotopes of redox-sensitive elements (Se, Mo, Fe, etc.) have played an important role. In comparison, the use of stable isotopes of some disperse elements (Ge, Cd, Tl) in tracing the paleo-oceanic environment was overlooked for years. But these elements have their own special recycling mechanism in the marine system, and thus, the trace of the stable isotopes of these elements may provide potential geological implications for the paleo-oceanic environment. Their sources and sinks are simple in the marine system, moreover, both inorganic and organic adsorption could control their isotopic fractionations.