Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips

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• 作者：Jordi Caballé ; -Serrano ; Kosaku Sawada ; Richard J. Miron ; Dieter D. Bosshardt ; Daniel Buser and Reinhard Gruber
• 刊名：Clinical Oral Implants Research
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：28
• 期：2
• 页码：236-241
• 全文大小：1217K
• ISSN：1600-0501

文摘

Collagen membranes serve as barriers to separate bone grafts from soft tissues. Bone grafts harvested with a bone scraper release growth factors activating transforming growth factor-β (TGF-β) signaling in mesenchymal cells. The aim of the present pilot study was to determine whether collagen membranes adsorb molecules from bone-conditioned medium (BCM) with the capacity to provoke the expression of TGF-β target genes in vitro.