Comparative effectiveness of epsilon-aminocaproic acid and tranexamic acid on postoperative bleeding following cardiac surgery during a national medication shortage
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- 作者：Kevin P. Blaine ; MD ; MPH ; kevin.blaine@nih.gov" class="auth_mail" title="E-mail the corresponding author (Resident Physician) ; Christopher Press ; MD (Resident Physician) ; Ken Lau ; MD1 (Resident Physician) ; Jan Sliwa ; MD2 (Resident Physician) ; Vidya K. Rao ; MD (Clinical Assistant Professor) ; Charles Hill ; MD (Clinical Assistant Professor ; Associated Critical Care Director)
- 关键词：ε-aminocaproic acid ; Tranexamic acid ; Blood conservation ; Perioperative bleeding ; Cardiac surgery
- 刊名：Journal of Clinical Anesthesia
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：516-523
- 全文大小：287 K
文摘
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Epsilon-aminocaproic and tranexamic acid are compared after cardiac surgery.
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Neither drug showed benefit in reducing postoperative bleeding or transfusions.
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Patients receiving aminocaproic acid required more rescue hemostatic agents.