Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity

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• 作者：Justin Flaven-Pouchon^b ; Jean-Pierre Farine^a ; John Ewer^b ; ^{john.ewer@uv.cl} ; Jean-Franç ; ois Ferveur^a ; ^{jean-francois.ferveur@u-bourgogne.fr}
• 关键词：Molting ; Eclosion ; Exoskeleton ; Insect ; Neurohormone ; cis-Vaccenyl acetate
• 刊名：Insect Biochemistry and Molecular Biology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：79
• 期：Complete
• 页码：87-96
• 全文大小：2742 K
• 卷排序：79

文摘

After adult emergence the insect cuticle is tanned, then further waterproofed by waxes and cuticular hydrocarbons (CHs). In D. melanogaster the CH content increases greatly during the first days of adult life; its composition is sex specific. Mutations in the bursicon receptor, rickets (rk), cause dramatic increases in the levels of CHs. These increases are mostly abrogated by mutations in the desaturase1 (desat1) gene. Our findings suggest that bursicon is involved in the maturation of the CH profile of adult flies.