文摘
The view that rapidly growing tumors are more lethal has remained almost axiomatic for decades. Rapid growth and metastases formation are often different outcomes of complex integrated molecular events. In humans interval cancers are more rapidly growing than cancers unaffected by screening. Cancers of the breast, cervix and large bowel, do not support the theory that rapidly growing cancers are more lethal. Existing evidence provide no support for treating interval cancers more aggressively than non-interval cancers.