RA showed an aggregation behavior (c.m.c. of 35 μM at pH 8 and 25 °C) which could be modified by the presence of CD.
The RA/CD complexes presented a 1:1 stoichiometry and the KF was dependent on pH, temperature and type of CD.
The pKa calculated for RA was 4.31.
Molecular docking provided further insights about the interactions in the complexes.