Cerebral Salt Wasting in Status Epilepticus: Two Cases and Review of the Literature

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• 作者：Tamer Ç ; elik ; MD^a ; Orkun Tolunay ; MD^b ; ^{orkuntolunay@yahoo.co.uk" class="auth_mail} ; 陌lknur Tolunay ; MD^c ; Ü ; mit Ç ; elik ; MD^d
• 关键词：cerebral salt wasting ; status epileptius ; hyponatremia ; syndrome of inappropriate antidiuretic hormone secretion
• 刊名：Pediatric Neurology
• 出版年：April, 2014
• 年：2014
• 卷：50
• 期：4
• 页码：397-399
• 全文大小：236 K

文摘

Background

Cerebral salt wasting is a hypovolemic hyponatremia state, caused by natriuresis and diuresis. The most important element of treatment is to replace the volume and sodium loss and improve the current clinic.

Patients

We present two children who were treated in the intensive care unit who subsequently developed cerebral salt wasting. Diagnosis was based on hyponatremia associated with high urinary sodium excretion and inappropriately high urine output in the presence of dehydration. As part of the treatment, one patient was given fluid and sodium replacement, measures that were insufficient in the other patient, who also required fludrocortisone treatment.

Conclusion

The status epilepticus may be involved in the etiology of cerebral salt wasting. In both patients, cerebral salt wasting was detected in the posttreatment follow-up evaluations. Cerebral salt wasting is particularly likely to occur in individuals with status epilepticus, and the electrolyte and hydration status of these patients should be monitored closely, even after the convulsions are taken under control.