CXCL12 localization in sheep during early gestation and after ART is discussed.
CXCL12 is localized in endometrial stroma, endometrial glands, and trophoblast cells.
Greater CXCL12 protein in trophoblast on days 22 and 24 compared to 18, 20, and 28.
Greater CXCL12 protein in naturally bred ewes compared to ART.
Decreased CXCL12 in trophoblast of ART embryos may compromise placentation.