Self-assembled high-strength hydroxyapatite/graphene oxide/chitosan composite hydrogel for bone tissue engineering
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- 作者：Peng Yua ; Rui-Ying Baoa ; Xiao-Jun Shib ; shixj83@163.com" class="auth_mail" title="E-mail the corresponding author ; Wei Yanga ; weiyang@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Ming-Bo Yanga
- 关键词：Graphene oxide ; Hydroxyapatite ; Chitosan ; Composite hydrogel ; Bone tissue engineering
- 刊名：Carbohydrate Polymers
- 出版年：2017
- 出版时间：2 January 2017
- 年：2017
- 卷：155
- 期：Complete
- 页码：507-515
- 全文大小：4381 K
文摘
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GO, HA and CS self-assemble into composites with an oriented microstructure.
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The self-assembly was performed under simultaneous crosslinking and reduction.
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HA was well loaded and fixed in the composite.
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The composite hydrogels show balanced strength and toughness.
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The composite hydrogels possess high porosity and large pore size.