Clinical study of cerebrospinal fluid neuropeptides in patients with primary trigeminal neuralgia
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Expressions of CGRP, SP, VIP and β-endorphin in CSF and peripheral blood were investigated.

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20 patients with primary TN were included and four types of samples were collected.

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The four neuropeptides have different level in CSF than control samples.

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Disease onset and duration has little effects on the productions and release of CGRP, SP, β-endorphin and VIP.

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