Ultrasensitive detection of influenza viruses with a glycan-based impedimetric biosensor
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- 作者：Andrá ; s Hushegyia ; Dominika Pihí ; ková ; a ; Tomas Bertoka ; Vojtech Adamb ; René ; Kizekb ; Jan Tkaca ; Jan.Tkac@savba.sk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biosensors ; Electrochemical impedance spectroscopy ; Glycans ; Influenza virus ; Lectins ; SAMs
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：79
- 期：Complete
- 页码：644-649
- 全文大小：660 K
文摘
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Construction of an ultrasensitive and highly selective impedimetric glycan biosensor.
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Lectin could be detected down to 5 aM level.
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Influenza viruses H3N2 were detected down to a level of 13 virus particles in 1 μl.
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The glycan biosensor is the most sensitive glycan based device described so far.
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Atomic force microscopy revealed surface morphology of a single virus particle.