Recent developments of 2-aminothiazoles in medicinal chemistry
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- 作者：Debasis Das ; debasisdas@chemconfidence.com" class="auth_mail" title="E-mail the corresponding author ; dasdebasis@redifffmail.com" class="auth_mail" title="E-mail the corresponding author ; Papiya Sikdar ; Moumita Bairagi
- 关键词：2-Aminothiazole ; Thiazole ; Review ; Bioactive ; Drugs ; Medicinal chemistry ; Pharmacological activity
- 刊名：European Journal of Medicinal Chemistry
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：109
- 期：Complete
- 页码：89-98
- 全文大小：1882 K
文摘
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2-Aminothiazole is an important and versatile scaffold in drug design and discovery.
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2-Aminothiazole -based compounds have been shown diverse biological activities.
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Many 2-aminothiazoles are known as anticancer, antimicrobial, anticonvulsant and antidiebatic agents.
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Newly identified 2-aminothiazoles in recent years and their application in medicinal chemistry are summarized in the review.