Structural, analytical and DSC references to resolution of 2-methoxy-2-phenylacetic acid with chiral 1-cyclohexylethylamines through gas-antisolvent precipitation

详细信息    查看全文

• 作者：Amit D. Zodge^a ; Petra Bombicz^b ; Edit Szé ; kely^a ; Gyö ; rgy Pokol^c ; Já ; nos Madará ; sz^c ; ^{madarasz@mail.bme.hu}
• 关键词：Chiral resolution ; (S)-(+)-O-methylmandelic acid ; Crystal structure ; (S)-1-cyclohexylethylammonium (S)-2-methoxy-2-phenylacetate ; Single crystal and powder X-ray diffraction (XRD) ; FTIR spectroscopy ; Differential scanning calorimetry (DSC) ; Binary and ternary melting phase diagrams ; Eutectic compositions and temperatures ; Structure-property relationship
• 刊名：Thermochimica Acta
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：648
• 期：Complete
• 页码：23-31
• 全文大小：2638 K
• 卷排序：648

文摘

Pure components in the given resolution system are sought and studied. Detailed analytical (XRD, FTIR, and DSC) features of all pure substances are compared. Single crystal X-ray structure of two compounds of this system has been determined. Structural implications are drawn for salts without known structures based on analytical features. Binary and ternary eutectic phase diagrams in the resolution system are constructed.