10">Indolin-2-one derivatives 3a-h and 5i-x were synthesized.
15">Compounds 3a-e, 5i-l, 5q-r were screened for in vitro anti-proliferation and genotoxicity.
Growth inhibition was up to 82.05 at 10−5 M concentration.
Among the tested compounds 3a-b, 3e exhibited promising anti-proliferative and genotoxic activity.