Comparison of Outcomes of Hematopoietic Cell Transplants from T-Replete Haploidentical Donors Using Post-Transplantation Cyclophosphamide with 10 of 10 HLA-A, -B, -C, -DRB1, and -DQB1 Allele-Matched Unrelated Donors and HLA-Identical Sibling Donors: A Multivariable Analysis Including Disease Risk Index
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- 作者：Asad Bashey1 ; abashey@bmtga.com" class="auth_mail" title="E-mail the corresponding author ; Xu Zhang2 ; Katelin Jackson1 ; Stacey Brown1 ; Michelle Ridgeway1 ; Melhem Solh1 ; Lawrence E. Morris1 ; H. Kent Holland1 ; Scott R. Solomon1
- 关键词：Haploidentical ; T-replete ; Post-transplantation cyclophosphamide ; Alternative donors
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：22
- 期：1
- 页码：125-133
- 全文大小：918 K
文摘
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T-replete grafts from haploidentical and MUD donors produce similar survival.
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Chronic GVHD is lower following haploidentical than MUD donor transplants.
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Less chronic GVHD in haploidentical transplants is independent of PBSC vs BM source.
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These results are confirmed in multivariate analysis.