Telomeres and telomerases as drug targets

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• 作者：Rezler ; Evonne M. ; Bearss ; David J. ; Hurley ; Laurence H.
• 关键词：Telomeres ; Telomerase ; G-Quadruplex ; hTERT ; hTR ; Antisense ; Cancer Biology ; Pharmacology ; Cell biology
• 刊名：Current Opinion in Pharmacology
• 出版年：2002
• 出版时间：August 1, 2002
• 年：2002
• 卷：2
• 期：4
• 页码：415-423
• 全文大小：241 K

文摘

Initial disappointment following the first trials of telomerase inhibitors as anti-cancer agents has dissipated with recent promises that more specific inhibitors of telomerase activity are soon to enter clinical trials.