The effects of ketogenic diet on the Th17/Treg cells imbalance in patients with intractable childhood epilepsy
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- 作者：Fen-Fen Ni ; Cheng-Rong Li ; shenzhen81111@163.com" class="auth_mail" title="E-mail the corresponding author ; Jian-Xiang Liao ; Guo-Bing Wang ; Su-Fang Lin ; Yu Xia ; Jia-Lun Wen
- 关键词：Ketogenic diet ; Intractable epilepsy ; Th17 cells ; Treg cells
- 刊名：Seizure
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：17-22
- 全文大小：1091 K
文摘
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Th17/Treg cell imbalance exists in intractable childhood epilepsy (IE).
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Abnormal mTOR/HIF-1α signaling pathway affects Th17/Treg balance in IE.
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Over-expression of HIF-1α may be due to abnormal expression of mTOR in IE.
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KD can restore the mTOR/HIF-1α signaling pathway to a normal level in IE.