Divergent effects of isolation rearing on prepulse inhibition, activity, anxiety and hippocampal-dependent memory in Roman high- and low-avoidance rats: A putative model of schizophrenia-relevant features
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- 作者：Ignasi Oliverasa ; Ignasi.oliveras@uab.cat" class="auth_mail" title="E-mail the corresponding author ; Ana Sá ; nchez-Gonzá ; leza ; Maria Antonietta Piludub ; Cristina Gerbolesa ; Cristó ; bal Rí ; o-Á ; lamosa ; Adolf Tobeñ ; aa ; Alberto Ferná ; ndez-Teruela ; Albert.fernandez.teruel@uab.cat" class="auth_mail" title="E-mail the corresponding author
- 关键词：IR ; Isolation rearing ; RHA-I ; Roman high-avoidance rats ; RLA-I ; Roman low-avoidance rats ; PPI ; Prepulse inhibition ; MWM ; Morris water maze
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：314
- 期：Complete
- 页码：6-15
- 全文大小：727 K
文摘
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Isolation rearing induces differential effects in RHA-I and RLA-I rats.
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Isolation rearing induces PPI deficits, hyperactivity and anxiety in RHA-I rats.
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Isolation rearing induces spatial reference memory deficits in RHA-I rats.
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Isolation rearing induces spatial working memory deficits in RLA-I rats.
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RHA-I rats may be a valid model for schizophrenia-relevant features.