刊名:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
出版年:2017
出版时间:February 2017
年:2017
卷:1864
期:2
页码:440-448
全文大小:1670 K
卷排序:1864
文摘
MNRR1 (CHCHD2) is a stress regulator functioning in both mitochondria and nucleus In mitochondria MNRR1 binds to cytochrome c oxidase (COX) Binding to COX is promoted by tyrosine phosphorylation Phosphorylation is carried out by Abl2 kinase (ARG) MNRR1 may be a modifier gene in a family with Charcot-Marie-Tooth disease type 1A