Intrinsic features of the CD8α∿/sup> dendritic cell subset in inducing functional T follicular helper cells
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- 作者：Changsik Shina ; 1 ; Jae-A Hana ; 1 ; Bongseo Choia ; Yoon-Kyoung Choa ; b ; Yoonkyung Doa ; Seongho Ryuc ; ryu@sch.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dendritic cell subset ; T follicular helper cell ; Localization ; Cytokine ; Cellular immunity ; Humoral immunity
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：172
- 期：Complete
- 页码：21-28
- 全文大小：3473 K
文摘
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Pre-Tfh cells are found proximal to CD8α− DCs in the MZ bridging channels.
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The role of IL-6 secreted from CD8α− DCs is minor in inducing Tfh cells.
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CD8α− DCs dominantly induce Tfh cells over other APCs.