刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
出版时间:January 2017
年:2017
卷:1861
期:1
页码:3237-3257
全文大小:4494 K
卷排序:1861
文摘
Changed glycosylation of CAMs is essential for their maturation, translocation to the cell surface and function. Altered E-cadherin glycosylation influences the early step of neoplastic transformation. Altered N-cadherin glycosylation influences neoplastic cells migration and invasion. Altered integrins and Ig-CAMs glycosylations influence each step of the metastatic cascade.