Effect of drying and loading methods on the release behavior of ciprofloxacin from starch nanoparticles
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- 作者：Aimin Shia ; b ; Dong Lib ; Hongzhi Liua ; Benu Adhikaric ; Qiang Wanga ; wangqiang06@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Starch nanoparticles ; Biological macromolecule ; Controlled release kinetics ; Ciprofloxacin ; Coating ; Adsorption
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：87
- 期：Complete
- 页码：55-61
- 全文大小：957 K
文摘
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Ciprofloxacin was loaded in starch nanoparticles using coating and adsorption methods.
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Loading methods significantly affected the amount of ciprofloxacin upload.
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Loading methods significantly affected the release kinetics of ciprofloxacin.
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Drying methods did not affect the amount of drug upload but release rate was affected.
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A double decay exponential kinetics model fitted the release of ciprofloxacin with R2 > 0.97