Human leukocyte antigen (HLA)-binding epitopes dataset for the newly identified T-cell antigens of Mycobacterium immunogenum

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• 作者：Harish Chandra ; Jagjit S. Yadav ; ^{jagjit.yadav@uc.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Immunoinformatics ; T-cell antigen ; T-cell epitopes ; HLA-I ; HLA-II ; Mycobacterium immunogenum ; Mycobacterium tuberculosis ; Hypersensitivity pneumonitis
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：8
• 期：Complete
• 页码：1069-1071
• 全文大小：158 K

文摘

The dataset described herein is related to our article entitled “T-cell antigens of Mycobacterium immunogenum (MI), an etiological agent of occupational hypersensitivity pneumonitis’’ (Chandra and Yadav, 2016) [1]. The data include in silico-predicted T-cell epitopes of the T-cell antigens AgA and AgD of MI predicted to bind to HLA-I or HLA-II alleles. Data on two reference T-cell antigens ESAT-6 and CFP-10 of Mycobacterium tuberculosis H37Rv are included for comparison. The data for each antigen include the predicted epitope׳s amino acid sequence, its first amino acid position, and its ability to bind HLA-I or HLA-II allele(s).