Hypothalamic expression of inflammatory mediators in an animal model of binge eating

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• 作者：Silvia Alboni^a ; ^{silvia.alboni@unimore.it} ; ^{salboni75@gmail.com} ; Maria Vittoria Micioni Di Bonaventura^b ; Cristina Benatti^a ; Maria Elena Giusepponi^b ; Nicoletta Brunello^a ; Carlo Cifani^b
• 关键词：Binge eating ; Stress ; Food restriction ; Cytokine systems ; Gene expression ; Hypothalamus
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：320
• 期：Complete
• 页码：420-430
• 全文大小：1840 K
• 卷排序：320

文摘

Food-restricted rats stressed during non-estrus develop binge eating (BE) behavior. BE is associated to changes in mRNA levels of inflammatory markers in hypothalamus. INOS mRNA increases in the anterior-tuberal hypothalamus of BE rats. IL-18/IL-18R system is down-regulated in hypothalamus of BE rats.