Investigation of relationship between 2,3-butanediol toxicity and production during growth of Paenibacillus polymyxa
详细信息 查看全文
- 作者：Christopher Chukwudi Okonkwoa ; Victor Ujorb ; Thaddeus Chukwuemeka Ezejia ; ezeji.1@osu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Paenibacillus polymyxa ; Levo-2 ; 3-butanediol ; Exopolysaccharide ; acetoin ; 1 ; 3- butadiene
- 刊名：New Biotechnology
- 出版年：2017
- 出版时间：25 January 2017
- 年：2017
- 卷：34
- 期：Complete
- 页码：23-31
- 全文大小：1729 K
文摘
- •
Levo-2,3-butanediol (2,3-BD)-mediated feed-back inhibition is a major physiological impediment to 2,3-BD yield.
- •
Increased levo-2,3-BD concentration in the fermentation medium triggers backward conversion of 2,3-BD to acetoin.
- •
Levo-2,3-BD mediated toxicity engenders increase in meso-2,3-BD accumulation during fermentation by P. polymyxa.
- •
Meso-2,3-BD isomer is less inhibitory to P. polymyxa than the levo isomer.
- •
Increase in levo-2,3-BD concentration decreases glucose utilization by P. polymyxa.