Chemical and biological characterization of polysaccharides isolated from Ilex paraguariensis A. St.-Hil.

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• 作者：Daniele Maria-Ferreira^a ; ¹ ; Nessana Dartora^b ; ¹ ; Luisa Mota da Silva^a ; Isabela Tiemy Pereira^a ; Lauro Mera de Souza^b ; Daniel Suss Ritter^b ; Marcello Iacomini^b ; Maria Fernanda de Paula Werner^a ; Guilherme Lanzi Sassaki^b ; ^{sassaki@ufpr.br} ; Cristiane Hatsuko Baggio^a ; ^{crisbaggio@gmail.com} ; ^{crisbaggio@hotmail.com}
• 关键词：Ilex paraguariensis ; Maté ; Polysaccharides ; Arabinogalactan ; Gastroprotective ; Gastric lesions
• 刊名：International Journal of Biological Macromolecules
• 出版年：2013
• 出版时间：August, 2013
• 年：2013
• 卷：59
• 期：Complete
• 页码：125-133
• 全文大小：1387 K

文摘

The potential gastroprotection of polysaccharides (SP) isolated from mat¨¦ (Ilex paraguariensis) leaves of different growth stages, under different sunlight conditions and of processing methods were evaluated. The SP consist of type I arabinogalactan (AG1) containing a (1¡ú4)-linked ¦Â-Galp chain, with substituents of arabinosyl units at O-6. This arabinogalactan seems to be attached to rhamnosyl units from a RG1, via 1¡ú4 linkage. Oral administration of SP1, SP9, SP10, SP11 and SP12 inhibited the gastric lesions induced by ethanol in rats. Altogether, the present data indicate the therapeutic role of mat¨¦ polysaccharides against gastric lesion and propose its use or of its crude plant extract as a phytotherapic medicine.