Enteric Viruses Ameliorate Gut Inflammation via Toll-like Receptor 3 and Toll-like Receptor 7-Mediated Interferon-β Production
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- 作者：Jin-Young Yang1 ; 9 ; Min-Soo Kim2 ; 9 ; Eugene Kim1 ; 9 ; Jae Hee Cheon3 ; 9 ; Yong-Soo Lee1 ; Yeji Kim1 ; Su-Hyun Lee1 ; Sang-Uk Seo4 ; Seung-Ho Shin5 ; Sun Shim Choi5 ; Bumseok Kim6 ; Sun-Young Chang7 ; Hyun-Jeong Ko8 ; Jin-Woo Bae2 ; baejw@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Mi-Na Kweon1 ; mnkweon@amc.seoul.kr" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：19 April 2016
- 年：2016
- 卷：44
- 期：4
- 页码：889-900
- 全文大小：3191 K
文摘
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Pre-treatment with an antiviral cocktail results in severe colitis
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Treatment with TLR3+7 agonists and inactivated rotavirus ameliorates colitis
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Tlr3−/−Tlr7−/− mice are more susceptible to colitis
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TLR3+7 agonists stimulate IFN-β secretion by pDCs from inflamed colon