Exposure to mild stress and brain derived neurotrophin factor (BDNF) immunoreactivity in the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei: Comparison between aged and adult rats
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- 作者：Ewa Badowska-Szalewska ; ewabadowska@gumed.edu.pl ; Beata Ludkiewicz ; Rafał Krawczyk ; Janusz Moryś
- 关键词：Brain derived neurotrophin factor ; Mild stress ; Hypothalamus ; Adulthood ; Ageing
- 刊名：Journal of Chemical Neuroanatomy
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：57-64
- 全文大小：1812 K
- 卷排序：78
文摘
The effect of acute and chronic stress on BDNF-immunoreactivity (-ir) was studied. Forced swim did not affect BDNF in hypothalamic PVN and SON of adult and aged rats. Acute high-light open-field (HL-OF) led to decrease in BDNF-ir in PVN of aged rats. Acute HL-OF caused an increase in BDNF-ir neurons in SON of adult rats. Age-related decrease in BDNF-ir in PVN and/or SON of HL-OF stressed rats was noted.