Slx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic Progression
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- 作者：Yee Mon Thu1 ; Susan Kaye Van Riper2 ; LeeAnn Higgins1 ; Tianji Zhang1 ; Jordan Robert Becker1 ; Todd William Markowski1 ; Hai Dang Nguyen1 ; 3 ; Timothy Jon Griffin1 ; Anja Katrin Bielinsky1 ; bieli003@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：10 May 2016
- 年：2016
- 卷：15
- 期：6
- 页码：1254-1265
- 全文大小：3610 K
文摘
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Replication-deficient mcm10 mutants rely on the SUMO network and Slx5/8 for survival
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Quantitative changes in the mcm10 mutant SUMO proteome are observed
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CPC components Bir1 and Sli15 are possible targets of the Slx5/8 pathway
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Slx5/8 counteracts mitotic checkpoint activation under moderate replication stress