Preservation of Gene Duplication Increases the Regulatory Spectrum of Ribosomal Protein Genes and Enhances Growth under Stress
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- 作者：Julie Parenteau1 ; Mathieu Lavoie1 ; Mathieu Catala1 ; Mustafa Malik-Ghulam1 ; Jules Gagnon1 ; Sherif Abou Elela1 ; sherif.abou.elela@usherbrooke.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：ribosome ; duplicated genes ; ribosomal proteins ; intergene regulation ; ribosome code ; ribosome heterogeneity ; UTR ; antibiotic resistance ; hygromycin
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：22 December 2015
- 年：2015
- 卷：13
- 期：11
- 页码：2516-2526
- 全文大小：2492 K
文摘
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Duplicated ribosomal protein genes (RPGs) are asymmetrically expressed and regulated
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Transcription termination regulates the expression of non-intron-containing RPGs
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Differences in expression levels enforce the subfunctionalization of duplicated RPGs
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Duplication of RPGs improves cell fitness and growth under stress