Accurate assessment of the weight of evidence for DNA mixtures by integrating the likelihood ratio

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• 作者：Klaas Slooten^a ; ^b ;
• 关键词：Likelihood ratios ; DNA mixtures ; Semi-continuous model ; Allelic dropout ; Low template DNA ; Deconvolution ; Weight of evidence
• 刊名：Forensic Science International: Genetics
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：27
• 期：Complete
• 页码：1-16
• 全文大小：1387 K
• 卷排序：27

文摘

We apply integration over the dropout probabilities to the semi-continuous mixture evaluation model. We thus obtain the LR as a weighted average over all dropout probabilities. We show we accurately recover the LR that would be obtained with the correct parameters. The method further objectifies mixture evaluation by being data driven. We lessen the need for expert assessment of dropout probabilities and the number of donors.