High hair selenium mother to fetus transfer after the Brazil nuts consumption

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• 作者：B. Momčilović^a ; ^{berislav.momcilovic@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; J. Prejac^b ; ^{juraj.prejac@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; V. Vi&scaron ; njević^a ; ^{vjeranv@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; S. Brundić^a ; ^{sanja.brundic@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; A.A. Skalny^c ; ^{andrey.skalny@orc.ru" class="auth_mail" title="E-mail the corresponding author} ; N. Mimica^d ; ^{ninoslav.mimica@bolnica-vrapce.hr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Hair Se ; Brazil nuts ; Pregnancy ; Lactation ; Transplacental Se transfer ; Fetus/infant
• 刊名：Journal of Trace Elements in Medicine and Biology
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：33
• 期：Complete
• 页码：110-113
• 全文大小：639 K

文摘

Lactating mother and her two month old healthy daughter (APGAR 10) gave their scalp hair for a multielement profile analysis; 25 elements were analyzed with the ICP MS. Mother’s hair was divided into 5 cm long segment proximal to the scull (Young), and the distal segment further up to the hair tip (Old). One centimeter of hair records one month of the metabolic activity of the bioelements in the body. Mother’s Young hair and daughters hair have 2.70 and 9.74 μg g⁻¹ Se, a distinctly higher Se concentrations than the Old hair of 0.87 μg g⁻¹. The adequate hair Se concentrations in Croatia women population vary from 0.08 to 0.63 μg g⁻¹; values below or above that range indicate deficiency or excess, respectively. Dietary recall revealed that during the last trimester of pregnancy and over a period of a week, the mother has consumed 135 g of Brazil nuts (Bertholletia excelsa) (BN); BN is an exceptionally rich Se dietary source. The amount of Se in BN varies and one week consumption of 135 g of BN may result in Se daily intake of 367 to 492 μg g⁻¹ day⁻¹ over a period of seven consecutive days, and what is about or exceeds the Upper Limit of daily selenium intake of 400 μg⁻¹ g⁻¹. The excessively high infant hair Se mirrored a natural high mother to fetus transplacental transfer of bio elements in the last trimester of pregnancy. The potential toxicological risks of such a high Se transfer remains to be elucidated.