We define counting and cocycle enhancement invariants of virtual knots using parity biquandles. The cocycle invariants are determined by pairs consisting of a biquandle 2-cocycle d="mmlsi1" class="mathmlsrc">data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S0166864116301286&_mathId=si1.gif&_user=111111111&_pii=S0166864116301286&_rdoc=1&_issn=01668641&md5=f39719e8e08e242b01874818d816db0a" title="Click to view the MathML source">ϕ0dden">de"> and a map d="mmlsi2" class="mathmlsrc">data-mathURL="/science?_ob=MathURL&_method=retrieve&_eid=1-s2.0-S0166864116301286&_mathId=si2.gif&_user=111111111&_pii=S0166864116301286&_rdoc=1&_issn=01668641&md5=537d32b62473e2d004beb99376af49f9" title="Click to view the MathML source">ϕ1dden">de"> with certain compatibility conditions leading to one-variable or two-variable polynomial invariants of virtual knots. We provide examples to show that the parity cocycle invariants can distinguish virtual knots which are not distinguished by the corresponding non-parity invariants.