文摘
Treatment with SNAP, a nitric oxide donor, caused a dose-dependent inhibition of spontaneous uterine contractility. The effect of SNAP treatment on uterine contractility was not influenced by age or weight of the mare. The effect was also not influenced by stage of estrous cycle, uterine histology grade, or uterine muscle layer. Stage of estrous cycle, uterine histology grade, and age had significant main effects on spontaneous uterine contractility. This study indicates that nitric oxide causes a dose-dependent inhibition of spontaneous uterine contractility in the mare.