The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation
文摘
Platelet NLRP3 promotes platelet activation, aggregation, and in vitro thrombosis. The NLRP3 inflammasome is upregulated in activated platelets. Platelet bruton's tyrosine kinase controls the identified NLRP3-dependent effects.