MAGE-D2 is a cytoplasmic and nucleoplasmic protein that accumulates in the nucleoli.
MAGE-D2 is a highly mobile nucleolar protein which interacts with nucleolin.
MAGE-D2 localization varies during cell cycle in a different manner than nucleolin.
The arginine-rich domain of MAGE-D2 encompasses several NLS and NoLS.
After nucleolar stress, MAGE-D2 accumulation in the nucleoplasm is p-ERK dependent.