Activation or blockade of 5-HT4 receptors impaired spatial memory.
CB1 receptors activation impaired spatial and novelty, while their blockade facilitated novelty.
Subthreshold dose of RS67333 restored ACPA response.
Subthreshold dose of RS23597 differently affect ACPA signaling.
Effective dose of AM251 blocked the effect of 5-HT4 agents on ACPA responses.