PI4KIIIβ/ACBD3/Aichi 3A reconstitution reveals direct activation of PI4KIIIβ by 3A ACBD3 sensitizes 3A-PI4KIIIβ activation, designed mutations disrupt complex HDX-MS defines the binding interfaces of ACBD3-PI4KIIIβ and 3A-ACBD3 Crystal structure of ACBD3 GOLD domain reveals a unique N terminus that binds with 3A