Double-lumen Inferior Vena Cava Catheters for Peripheral Stem Cell Apheresis and Transplantations

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• 作者：Haire ; William D. ; Stephens ; Lana C. ; Kotulak ; Gail D. ; Schmit-Pokorny ; Kim ; Kessinger ; Anne
• 刊名：Transfusion Science
• 出版年：1995
• 出版时间：March, 1995
• 年：1995
• 卷：16
• 期：1
• 页码：79-84
• 全文大小：464 K

文摘

No previously published studies have described double-lumen hemodialysis/apheresis catheters for use with continuous-flow apheresis collection of peripheral stem cell (PSC). We prospectively evaluated experiences with these catheters during both PSC collection and transplantation. Because of previously-described successful experiences with single-lumen apheresis catheters placed in the inferior vena cava, all catheters evaluated in this study were placed in this anatomic location. Our experience demonstrated high rates of thrombotic occlusion (65 % ) and catheter-related infections (15 % ). This method of access should not be considered optimal in its present state of use. Further investigation into preferred catheter design, anatomic location, and thrombosis prophylaxis during continuous-flow apheresis is warranted.