Topologically controlled hyaluronan-based gel coatings of hydrophobic grid-like scaffolds to modulate drug delivery
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- 作者：M. Arnal-Pastora ; 1 ; M. Pé ; rez-Garnesa ; 1 ; M. Monleó ; n Pradasa ; b ; A. Vallé ; s Llucha ; avalles@ter.upv.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hyaluronan ; Poly(ethyl acrylate) ; Scaffold ; Hydrogel coating ; Controlled release
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：140
- 期：Complete
- 页码：412-420
- 全文大小：1300 K
文摘
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Poly(ethyl acrylate) grid-like scaffolds were coated with hyaluronan (HA) gel.
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Controlled coating typologies were obtained by varying the HA concentration.
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Mechanical properties and swelling were correlated with the HA mass fraction.
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Their potential as drug release vehicle was proven using a protein model.