The abnormal status of uncarboxylated matrix Gla protein species represents an additional mortality risk in heart failure patients with vascular disease
详细信息 查看全文
- 作者：Otto Mayer Jra ; b ; mayero@fnplzen.cz" class="auth_mail" title="E-mail the corresponding author ; Jitka Seidlerová ; a ; b ; Jiří ; Vaněka ; Petra Karnosová ; a ; b ; Jan Bruthansa ; c ; Jan Filipovský ; a ; b ; Peter Wohlfahrtc ; d ; Renata Cí ; fková ; c ; d ; Jindra Windrichová ; e ; Marjo H.J. Knapenf ; Nadja E.A. Drummenf ; Cees Vermeerf
- 关键词：Matrix γ-carboxyl glutamate protein (MGP) ; Heart failure ; dp-ucMGP ; t-ucMGP ; Mortality ; Atherovascular disease
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：203
- 期：Complete
- 页码：916-922
- 全文大小：441 K
文摘
- •
Matrix Gla protein (MGP) is a natural calcification inhibitor.
- •
Abnormal uncarboxylated MGP species were associated with mortality risk.
- •
Highest risk represents co-incident abnormal MGP and brain natriuretic peptide.