Mitochondrial apoptotic pathway and inflammatory response particulate in QCT induced cell death in L02 cell.
Curcumin could effectively inhibit QCT induced iNOS/NO mediated inflammation via the inhibition of NF-kB pathway.
Curcumin could effectively inhibit QCT induced mitochondrial apoptotic pathway via the activation of Nrf2/HO-1pathway.
These foundings provide the important information for preventing QdNOs family members-induced cytotoxicity and apoptosis.