Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening
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- 作者：Ahmed M.O. Elbatsh1 ; 5 ; Judith H.I. Haarhuis1 ; 5 ; Naomi Petela2 ; Christophe Chapard2 ; Alexander Fish3 ; Patrick H. Celie3 ; Magda Stadnik3 ; Dejan Ristic4 ; Claire Wyman4 ; René ; H. Medema1 ; Kim Nasmyth2 ; Benjamin D. Rowland1 ; b.rowland@nki.nl" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：18 February 2016
- 年：2016
- 卷：61
- 期：4
- 页码：575-588
- 全文大小：4282 K
文摘
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Cohesin’s DNA release involves an asymmetric activity within its ATPase machinery
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DNA release is driven by the ATPase site proximal to the locking acetylation marks
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Cohesin’s DNA release is ATPase driven in yeast and humans
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Cohesin’s loading onto DNA is controlled by both of its ATPase sites