Non-invasive respiratory monitoring during wakefulness and sleep in pre- and postmenopausal women

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• 作者：Jenni Aittokallio ; Arho Virkki ; Tero Aittokallio ; Tarja Saaresranta ; Pä ; ivi Polo-Kantola and Olli Polo
• 关键词：Transcutaneous carbon dioxide ; End-tidal carbon dioxide ; Arterial oxyhemoglobin saturation ; Menopause ; Aging ; Sleep
• 刊名：Respiratory Physiology & Neurobiology
• 出版年：2006
• 出版时间：25 January 2006
• 年：2006
• 卷：150
• 期：1
• 页码：66-74
• 全文大小：248 K

文摘

Menopause and aging cause hormonal changes with respiratory consequences. The aim of the present study was to investigate the physiological changes in respiration during wakefulness and sleep across menopause in non-patient population using non-invasive measurements of blood and tissue gases. The arterial oxyhemoglobin saturation (SaO₂), heart rate, end-tidal partial carbon dioxide tension (EtCO₂) and transcutaneous partial carbon dioxide tension (TcCO₂) were measured during wakefulness and sleep in thirteen pairs of BMI-matched pre- and postmenopausal women. Postmenopausal women had lower SaO₂ during sleep than during wakefulness, whereas premenopausal women maintained their wakefulness SaO₂ levels also during sleep. EtCO₂ levels did not change either between wakefulness and sleep or between premenopausal and postmenopausal groups. TcCO₂ levels increased from wakefulness to sleep in both groups and the increase was greater in the postmenopausal group. The impact of sleep on the non-invasive measurements of blood and tissue gases is stronger in postmenopausal women.