Association between parental nativity and autism spectrum disorder among US-born non-Hispanic white and Hispanic children, 2007 National Survey of Children¡¯s Health

详细信息    查看全文

• 作者：Laura A. Schieve ; Ph.D.^a ; ^{LSchieve@cdc.gov} ; Sheree L. Boulet ; Dr.P.H.^a ; Stephen J. Blumberg ; Ph.D.^b ; Michael D. Kogan ; Ph.D.^c ; Marshalyn Yeargin-Allsopp ; M.D.^a ; Coleen A. Boyle ; Ph.D.^a ; Susanna N. Visser ; M.S.^a ; Catherine Rice ; Ph.D.^a
• 关键词：Autistic disorder ; Developmental disabilities ; Prevalence ; Population group ; Race ; Hispanic ; Place of birth
• 刊名：Disability and Health Journal
• 出版年：2012
• 出版时间：January, 2012
• 年：2012
• 卷：5
• 期：1
• 页码：18-25
• 全文大小：143 K

文摘

Background

Limited studies suggest the prevalence of autism spectrum disorders (ASD) varies by whether maternal and child birth country are discordant.

Objective/Hypothesis

We explored associations between ASD and maternal and paternal nativity in a sample of US-born non-Hispanic white (NHW, n = 37,265) and US-born Hispanic (n = 4,690) children in the 2007 National Survey of Children¡¯s Health (NSCH).

Methods

We assessed ASD prevalence within race-ethnicity and parental nativity subgroups. Prevalence ratios (aPR), comparing each group to NHW children with 2 US-born parents, were adjusted for child age, sex, and receipt of care in a medical home. Estimates were weighted to reflect US noninstitutionalized children. Standard errors were adjusted to account for the complex sample design.

Results

In NHW children with 2 US-born parents, ASD prevalence was 1.19 % ; estimates were similar for NHW children with a foreign-born mother or father. There was a striking heterogeneity between Hispanic children with 2 US-born versus 2 foreign-born parents (ASD prevalence 2.39 % versus 0.31 % , p = .05). Even after adjustment, PRs comparing ASD prevalence in Hispanic versus NHW children were vastly different for Hispanic subgroups, suggesting a substantially lower prevalence for Hispanic children with both parents foreign-born (aPR 0.2, 95 % confidence interval 0.1-0.5) and a higher prevalence for Hispanic children with both parents US-born (aPR 2.0 [0.8-4.6]).

Conclusions

Previous studies comparing ASD prevalence between NHW and Hispanic children based on a composite Hispanic grouping without consideration of parental nativity likely missed important differences between these racial-ethnic groups. Continuing efforts toward improving early identification in Hispanic children are needed.