Protective effect of different flavonoids against endothelial senescence via NLRP3 inflammasome
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- 作者：Chunhui Sun ; Xin Wang ; Guihong Zheng ; Shaohua Fan ; Jun Lu ; Zifeng Zhang ; Dongmei Wu ; Qun Shan ; Bin Hu ; Yuanlin Zheng ; ylzheng@jsnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endothelial senescence ; Flavonoids ; High glucose ; NLRP3 inflammasome ; Reactive oxygen species
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：26
- 期：Complete
- 页码：598-609
- 全文大小：3383 K
文摘
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Flavonoids prevent endothelial senescence induced by high glucose.
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Flavonoids eliminate ROS accumulation in senescent endothelial cells.
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Flavonoids inhibit cell senescence by blocking NLRP3 inflammasome activity.