Cancer cachexia induces remodeling of the heart.
Tumor-borne secreted factors mediate cardiomyocyte atrophy.
Selective cachexokines, including Bin1, Stx7, Minpp1, Gaa, Ccl2, Adamtsl4, and Atxn10 provoke aberrant cardiac FA metabolism.
Ataxin-10 levels are elevated under cachectic conditions in mice and tumor patients.