Synthesis, crystal structure, ABTS radical-scavenging activity, antimicrobial and docking studies of some novel quinoline derivatives
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- 作者：Sumaiya Tabassuma ; T.H. Suresha Kumaraa ; b ; suresha.kumara@gmail.com" class="auth_mail ; Jerry P. Jasinskic ; Sean P. Millikanc ; H.S. Yathirajand ; P.S. Sujan Ganapathye ; H.B.V. Sowmyaa ; Sunil S. Moref ; Gopalpur Nagendrappaa ; Manpreet Kaurd ; Gilish Josea
- 关键词：Vilsmeier&ndash ; Haack reaction ; Quinoline ; Single crystal X-ray structure ; Docking studies ; Antimicrobial studies ; ABTS Radical-scavenging activity
- 刊名：Journal of Molecular Structure
- 出版年：24 July 2014
- 年：2014
- 卷：1070
- 期：Complete
- 页码：10-20
- 全文大小：2151 K
文摘
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New series of 2-chloroquinolin-3-yl ester derivatives were synthesized.
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Chemical structures of the compounds were characterized by 1H NMR, 13C NMR, LCMS spectral analysis and elemental analysis.
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X-ray crystallographic study of 6a and 6e were carried out.
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In vitro antimicrobial and ABTS radical-scavenging activity screening were carried out.
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The docking studies were carried out.