Inheritance of steroid-independent male sexual behavior in male offspring of B6D2F1 mice
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- 作者：Christine M. McInnisa ; 1 ; cmcinnis1@partners.org" class="auth_mail" title="E-mail the corresponding author ; Paul J. Bonthuisb ; 2 ; Emilie F. Rissmanb ; 3 ; Jin Ho Parka ; b
- 关键词：Steroid-independent male sexual behavior ; B6D2F1 mouse ; Behavioral genetics ; APP ; Tau ; Synaptophysin
- 刊名：Hormones and Behavior
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：132-138
- 全文大小：573 K
文摘
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~ 30% B6D2F1 male mice demonstrate steroid-independent male sex behavior (SI-MSB).
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Elevated APP, tau, and synaptophysin impact SI-MSB.
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SI-MSB was found to be a heritable trait.
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This trait is passed down mainly from B6D2F1 mice that demonstrate SI-MSB.
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APP, tau, and synaptophysin were higher in B6D2F1 males and sires that show SI-MSB.