After introducing the methodology, we apply it to assess the impact of Carrier-Grade NAT (CGN), a technology that Internet Service Providers (ISPs) deploy to limit the usage of expensive public IP addresses. Since CGN may introduce connectivity issues and performance degradation, we process a large dataset of passive measurements collected from an ISP using CGN for part of its customers. We first extract detailed per-flow information by processing packets from live links. Then, we derive higher level statistics that are significant for the end-users, e.g., TCP connection setup time, HTTP response time, or BitTorrent average download throughput. At last, we contrast figures of customers being offered public or private addresses, and look for statistically significant differences. Results show that CGN does not impair quality of service in the analyzed ISP deployment. In addition, we use the collected data to derive useful figures for the proper dimensioning of the CGN and the configuration of its parameters in order to avoid impairments on end-users’ experience.